The "D:\" folder is determined by where you put the sabnzbd.ini file.
Obviously you put it in the root of D:
When sabnzbd.ini is in (example) d:\usenet, then all relative folders listed are relative to d:\usenet.
It's always possible to use a full path for any folder, if you choose so.
sabnzbd 0.4.4 wont recognize nzb files after some minutes of running
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Check your connection in Status and Interface settings window.
Use Test Server in Config > Servers.
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Re: sabnzbd 0.4.4 wont recognize nzb files after some minutes of running
Oh just realized now, maybe you want to know 
My sabnzbd.ini is in C:\Documents and Settings\~\Local Settings\Application Data\sabnzbd\
Nothing concerning sabnzbd is on D:\
My sabnzbd.ini is in C:\Documents and Settings\~\Local Settings\Application Data\sabnzbd\
Nothing concerning sabnzbd is on D:\
Re: sabnzbd 0.4.4 wont recognize nzb files after some minutes of running
Somehow SABnzbd doesn't pick up your user directory.
The "user" folders should by default be in "c:\documents and settings\USERNAME\My Documents".
Did you move the "My Documents" location?
The "user" folders should by default be in "c:\documents and settings\USERNAME\My Documents".
Did you move the "My Documents" location?
Re: sabnzbd 0.4.4 wont recognize nzb files after some minutes of running
OK, that's fine. Should not be a problem.